How do sarcomas spread

Soft tissue sarcoma can spread almost anywhere in the body. Where it is most likely to spread depends on factors such as the type of soft tissue sarcoma and where in the body the cancer started. If soft tissue sarcoma spreads, it may spread to the following: tissues or areas around where the cancer started lungs — especially for soft tissues sarcomas that start in the arms or legs liver — especially for soft tissue sarcomas that start in the abdomen bone brain nearby lymph nodes — rare site of metastases for most soft tissue sarcomas.

Home Cancer information Cancer types Soft tissue sarcoma If cancer spreads. If soft tissue sarcoma spreads. References American Society of Clinical Oncology.

Sarcomas of Specific Organs Guide. Net Guide Sarcomas of Specific Organs. Risk Factors. Symptoms and Signs. Stages and Grades. Types of Treatment. About Clinical Trials. Latest Research. Coping with Treatment. Follow-Up Care. Questions to Ask the Health Care Team. Additional Resources. View All Pages. Find a Cancer Doctor. Aorta, pulmonary artery, pulmonary vein large blood vessels coming out of the heart. Epithelioid hemangioendothelioma, solitary fibrous tumor, synovial sarcoma.

Endometrial stromal sarcoma, undifferentiated endometrial sarcoma, adenosarcoma, PEComa. So, it could be predicted that some genes expressed in a specific sarcoma might have prognostic significance or therapeutic targeting potential and molecular targets can be identified in the tumor or in the tumor microenvironment. The chemokine signaling demonstrated to be deeply implicated in sarcoma development as well as to have a significant role in development of metastatic disease, especially in directing tumor cells towards the preferential sites of metastases in sarcoma, lung and bone.

It is unsolved if the blood stream is a more favorable environment compared to lymphatic or if lymph nodes are more efficient in destroying metastatic sarcoma cells. But the comprehension of the regulatory mechanisms of the behavior of mesenchymal malignant tumors is at its dawn.